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Year 2007, Month 4 (Section Reviews, Page 680)

Ligands of the colchicine site of tubulin: a common pharmacophore and new structural classes

O. N. Zefirova,
A. G. Diikov, N. V. Zyk, and N. S. Zefirov

Structure—activity relationships for ligands of the colchicine site of tubulin were analyzed based on their common pharmacophore. The role of the elucidation of the three
dimensional structure of the colchicine site of tubulin on the development of studies aimed at the search for the ligands of this site is analyzed.

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