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ISSUE 10

Year 2007, Month 10 (Section Full Articles, Page 2105)

Conjugates of polyhedral boron compounds with carbohydrates 5. Synthesis of glycoconjugates of closo-ortho-carborane and N-acyl-β-lactosylamines with various spacers

L. M. Likhosherstov, O. S. Novikova, L. O. Kononov, A. V. Orlova, I. B. Sivaev, and V. I. Bregadze

Conjugates of β-lactosylamine derivatives bearing terminal amino groups in aglycon with ortho-carboranylacetic acid were synthesized. Five glycoconjugates with spacers of different length (from 9 to 18 atoms) and hydrophilicity containing di-, tri-, and pentapeptide fragments constructed of glycine and serine residues and spacers incorporating ethylenediamine and tartaric acid or tertiary amine residues were prepared.

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