Year 2005, Month 1 (Section Full Articles, Page 79)
Synthesis of hydroxyapatite by hydrolysis of α-Ñà3(ÐÎ4)2
O. V. Sinitsyna,(a) A. G. Veresov,(a) E. S. Kovaleva,(a) Yu. V. Kolen´ko,(a) V. I. Putlyaev,(b)* and Yu. D. Tretyakova,(b)
Conditions for hydroxyapatite (HAP) synthesis in aqueous solutions by hydrolysis of
α-Ñà3(ÐÎ4)2 were studied. Temperature exerts a substantial effect on the rate of α-Ca3(PO4)2
hydrolysis and also changes the morphology of the reaction products. At 40 °C, the plate-like
intersecting (perpendicular to the surface of the initial particles) crystals of HAP grow. Their
maximum size after the 24-h hydrolysis is 1—2 µm. Needle-like HAP crystals are formed upon
boiling of the suspension. The morphology observed for the HAP particles agrees well with the
conclusions obtained by analysis of the kinetics of tricalcium phosphate hydrolysis.
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