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ISSUE 1

Year 2005, Month 1 (Section Brief Communications, Page 257)

Synthesis of new derivatives of 5,6,7,8-tetrahydro-1,6-naphthyridines and their pharmacological properties

S. Z. Vatsadze,(a)* M. L. Kostochka,(a) V. P. Lezina,(b) V. G. Vinokurov,(b) P. M. Klodt,(b) and N. V. Zyk(a)

1,5-Dicarbonyl derivatives of piperidine and tropane were studied in the heterocyclization with hydroxylamine hydrochloride. All the 5,6,7,8-tetrahydro-1,6-naphthyridines obtained exhibit a pronounced analgesic effect.

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