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ISSUE 5

Year 2005, Month 5 (Section Full Articles, Page 1239)

Synthesis of substituted 1,2-di(alkylsulfonyl)indolizines. Molecular and crystal structure of 3-(4-f luorobenzoyl)-6-methyl-1,2-di(propylsulfonyl)indolizine*

N. E. Dontsova,(a)* V. N. Nesterov,(b) A. M. Shestopalov,(a) and V. P. Litvinov(a)

The reactions of substituted pyridinium salts with E-1,2-di(alkylsulfonyl)-1,2-dichloro- ethenes proceed regiospecifically. Heating of these reagents in chloroform in the presence of a threefold excess of Et3N affords substituted 1,2-di(alkylsulfonyl)indolizines in high yields. The structures of the reaction products were confirmed by physicochemical methods, including X-ray diffraction.

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