Year 2005, Month 9 (Section Brief Communications, Page 2226)
Mannich reaction in the synthesis of N,S-containing heterocycles.
1. Synthesis of novel derivatives of imidazo[2,1-b][1,3,5]thiadiazine*
K. A. Frolov,(a) V. V. Dotsenko,(a) S. G. Krivokolysko,(a) and V. P. Litvinov(b)*
Reactions of (Z )-5-benzylidene-2-thiohydantoin with formaldehyde and primary aromatic amines afforded novel derivatives of imidazo[2,1-b][1,3,5]thiadiazine in 50—69% yields.
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